
THE COGSPAN™
SYSTEM
ASSESSMENT · ROADMAP · DOMAIN GUIDELINES
Your yearly physical asks if you're sick.
We ask how well you're working, and how to keep it.
THE SILENT GAP™ ASSESSMENT
Your intrinsic capacity is the physical and mental reserve that shapes how well you'll live at 80. The patent-pending CogSpan™ System is the complete system for measuring and building it. The Silent Gap™ Assessment measures you. Ten Intrinsic Capacity Scores show where you stand. Your Roadmap tells you what to do. And every domain has its own follow-up guidelines, personalized to you.
HOW THE COGSPAN™ SYSTEM WORKS
One complete system, not just an assessment.
It starts with a few simple steps before your visit and one coordinated day of testing. Then you get your scores, your Roadmap, and personalized follow-up guidelines for every domain. Retest every year to see what is improving.
In person in Pasadena, or virtually from home.
1. Assess
THE ASSESSMENT
Silent Gap™ Assessment
Fasting labs and a detailed health questionnaire about 3 weeks ahead. Then one coordinated day of brain and body testing.
2. Score
THE COGSPAN™ SYSTEM
Ten scores, 0 to 100
The CogSpan™ System scores every result against optimal ranges, not just "normal," and combines them into ten Intrinsic Capacity Scores.
3. Roadmap
RESULTS VISIT
Your instructions
Dr. Anvekar walks you through every score and gives you your CogSpan™ Roadmap: what to do, and in what order, starting with your one to three lowest domains.
4. Guidelines
EVERY DOMAIN
Personalized follow-up
Every one of your ten domains has its own follow-up guidelines, and within them, guidelines personalized to your results. Then you retest every year.
What we measure in one coordinated day

How is your brain working right now?
Neurocognitive testing
Memory, attention, processing speed, executive function and cognitive flexibility.
Mood screening
Screening for anxiety, depression and PTSD, because mood and cognition move together.
Your cognitive baseline
A starting point to compare against every year. A screening tool, not a diagnosis.

How is your body working right now?
Strength, balance & mobility
Strength, gait, walking speed, lower-body endurance, mobility, balance and recovery.
Heart & blood vessels
Blood pressure, resting heart rate, oxygen and heart-rate response to standing. EKG when indicated.
Provider exam
A head-to-toe exam with a medication, supplement and preventive-care review.
Hormones
Hormonal symptoms reviewed, with hormone labs when clinically appropriate.

How is your metabolism working right now?
Advanced fasting labs
Glucose and insulin, cholesterol and heart risk, inflammation and immune balance. Billed to insurance.
Organs & nutrients
Nutrient status, kidney, liver and thyroid function, and urine markers of early kidney health.
Lifestyle & environment
A 100+ question health questionnaire. Add the Environmental Toxin Bundle for metals, mold, plastics and forever chemicals.
Testing is individualized to your age, sex, symptoms, medical history and medications.
A results visit with Dr. Anvekar to walk through every score.
Then your instructions, plus follow-up guidelines for every domain, personalized to you. Retested every year.
✓ Your 10 Intrinsic Capacity Scores ✓ Biological-age estimate ✓ Cognitive baseline
✓ Lab & performance patterns ✓ Your strongest areas ✓ Prescriptions when indicated
May include a brain MRI and neuroinflammation labs if your brain domain score is low, a meal app, sleep study, CGM, supplements, IV therapy, peptide or stem cell discussions and specialist referrals, as your results indicate.
Measure your health while it is still yours to shape.
Many of the changes that eventually lead to diabetes, cardiovascular disease, cognitive decline, frailty and other age-related conditions begin years or decades before a diagnosis can be made.
Don’t wait for disease to show up in your health story. Prevent it in the earliest stages.
The Silent Gap™: the years between feeling healthy and a diagnosis.
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Laboratory results may remain inside broad “normal” ranges
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Insulin resistance may begin before glucose becomes abnormal
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Muscle and cardiovascular fitness may decline before daily function changes
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Cognitive performance may shift before symptoms become obvious
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Inflammatory and metabolic patterns may emerge gradually
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Sleep, stress and recovery may begin influencing multiple body systems
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Several small changes may matter more together than any one result does alone
The goal of the Silent Gap Assessment is not to diagnose disease that is not present. It is to look for patterns, trends and areas moving away from optimal health while there is still time to pay attention.
Normal isn't always good enough.
A laboratory value may be technically normal while still becoming less favorable over time.
A single result may seem unimportant on its own but become more meaningful when considered alongside sleep, cognition, waist circumference, blood pressure, physical performance, family history and other measurement changes. Our model is designed to recognize these relationships.
Your 10 Intrinsic Capacity Scores
You receive concrete scores across:
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Brain
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Metabolic
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Sleep
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Cardiovascular
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Physical Function
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Inflammation
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Hormonal Health
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Mitochondrial and Oxidative Stress
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Purpose and Reserve
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Risk and Health Engagement
How the patent-pending CogSpan™ System scores you
Most physicals hand you a stack of separate results.
The CogSpan™ System looks at how they work together. Every data point is weighted by its importance to long-term health, standardized, and combined into ten Intrinsic Capacity Scores and one overall score.
Retest every year. Watch your scores move.
A single assessment shows where you stand today. Repeating your Silent Gap Assessment every year allows you to act as soon as one of your numbers move:
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Which scores are improving
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Which scores are stable
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Which areas are beginning to change
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Whether your health efforts are producing measurable progress
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Where additional evaluation may be worth considering
THE COGSPAN™ SYSTEM
Over 200 biomarkers · 10 Intrinsic Capacity Domains · 1 day of testing · Retested every year
Start here
Silent Gap
Assessment
& Roadmap
$1,495
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Want to know how your brain, body and metabolism are working right now
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No symptoms, or feeling "off" with normal labs
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Want a baseline with concrete numbers to track every year
Every assessment includes:
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Detailed online health questionnaire
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Fasting labs (billed to insurance) a few weeks before your visit, on site or via an electronic order to Quest
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One coordinated day of medical and performance testing
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Neurocognitive assessment
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Strength, balance, gait and mobility testing
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Comprehensive lifestyle assessment
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Provider examination and preventive-health review
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Your 10 Intrinsic Capacity Scores from the CogSpan™ System
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Your CogSpan™ Roadmap: a personal report and results visit with Dr. Anvekar
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Identification of one to three health domains that may deserve the most attention
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Prescriptions for imaging, studies, medications or hormones billed to your insurance if indicated
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May include subscription to a meal app, sleep study prescription, continuous glucose monitor, environmental products and toxins elimination instructions, supplements, IV therapy, peptide or stem cell discusssions, referrals to specialists or imaging, tips for improving your local indoor air and water quality and advanced detox protocols, all as needed per your results.
Go deeper
Upgrade
Bundles
Best for:
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Symptoms with no clear cause
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Initial Mini-quiz score less than 70
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Want a deeper look at what is driving your scores
Environmental Toxins
$999 add-on
Includes:
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Expanded 23 heavy metals testing
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Forever chemicals testing
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Advanced Mold testing
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Plastics testing
Metabolic Testing
$519 add-on
Includes:
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DEXA total body composition scan (muscle, fat and bone)
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Resting Metabolic Rate testing
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VO2 Max testing
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One year of the My Living Eats diet app, preloaded with the diet your provider prescribes with your Roadmap.
Follow Me
$599 add-on
A complete repeat of your Silent Gap Assessment at 3 or 6 months, without a new Roadmap. Just your 10 new scores, so you can see exactly what has changed.
Join Us
Longevity Membership
The assessment, every bundle, and four longevity care visits a year with Dr. Anvekar and her Longevity Nurse Practitioner. For this membership, you keep your own doctor for your primary care needs.
$299 monthly
12-month minimum
Includes two Silent Gap™ Assessment and CogSpan™ Roadmaps during the year (the Assessment plus the Follow Me bundle), the Metabolic Testing bundle (VO2 max, DEXA total body composition scan and resting metabolic rate), and the Environmental Toxins bundle.
Four longevity consults a year: two with Dr. Anvekar and two with Mardly, our longevity nurse practitioner
Longevity care consults, not primary care. Keep your current doctor.
Concierge Care Membership
Dr. Anvekar's private concierge practice
$499 monthly
12-month minimum
Includes your Silent Gap™ Assessment, powered by the CogSpan™ System, every year at the time of your preventative health comprehensive physical.
24/7 access to Dr. Anvekar for both longevity and primary care needs via email, text and phone calls.
Whole-health management, including hormones and prescriptions, with primary care visits throughout the year billed to your insurance.
10% off of every service or product throughout the year.
Only for residents of CA, UT or FL

"Your physical asks if you're sick. Your Silent Gap Assessment asks what you're capable of, and how to keep it."
DR. ALEXIS ANVEKAR, THE LIVING METHOD
THE COGSPAN™ SYSTEM
What to Expect

Virtually from your own Home
Mailed Assessment Kit containing examination equipment
Zoom visit with your clinician. Some upgrade bundle services can't be performed off-site.
Your timeline:
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4 weeks ahead (Environmental Toxin Bundle only):
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4 days of diet restrictions to prepare for environmental testing suite
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Collect overnight urine sample and mail to lab
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3 weeks ahead:
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Fasting blood draw
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Day of visit:
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Wear comfortable clothing ready to move
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Testing links will be emailed to you
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Zoom link for your movement tests with our staff will be emailed to you
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In-Person at our Pasadena Facility
In-Person
Assessment
Your timeline:
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4 weeks ahead (Environmental Toxin Bundle only):
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4 days of diet restrictions to prepare for environmental testing suite
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Collect overnight urine sample and mail to lab
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3 weeks ahead:
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Fasting blood draw
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Day of visit:
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Come in comfortable clothing ready to move for testing
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How We
Compare
This data is from published sources and is subject to change
